Links to Selection of Dr. Caporale's publications in the scientific literature.                

In Darwinian evolution, feedback from natural selection leads to biased mutations

Lynn H. Caporale and John Doyle

Ann N Y Acad Sci. 2013 Sep 13. doi: 10.1111/nyas.12235.
Overview of the creative genome: effects of genome structure and sequence on the generation of variation and evolution.
Caporale LH.Ann N Y Acad Sci. 2012 Sep;1267:1-10. doi: 10.1111/j.1749-6632.2012.06749.x.

Putting together the pieces: evolutionary mechanisms at work within genomes: can we suggest molecular underpinnings of punctuated equilibria and the Cambrian explosion?
Caporale LH.Bioessays. 2009 Jul;31(7):700-2. doi: 10.1002/bies.200900067. PMID: 19526531

It's not random anymore.Caporale LH.Bioessays. 2008 Apr;30(4):400-2. doi: 10.1002/bies.20747. PMID: 18348250

Darwin in the genome. Caporale L. Bioessays. 2005 Sep;27(9):984. PMID: 16108075

Natural selection and the emergence of a mutation phenotype: an update of the evolutionary synthesis considering mechanisms that affect genome variation. Caporale LH.Annu Rev Microbiol. 2003;57:467-85. Review. PMID: 14527288

Mutation is modulated: implications for evolution.Caporale LH.Bioessays. 2000 Apr;22(4):388-95. Review.PMID: 10723036 

Chance favors the prepared genome.
Caporale LH.Ann N Y Acad Sci. 1999 May 18;870:1-21. Review.PMID: 10415469 

Lessons from the most innovative genetic engineer.
Caporale LH.Nat Biotechnol. 1998 Oct;16(10):908-9. PMID: 9788342

Chemical ecology: a view from the pharmaceutical industry.
Caporale LH.Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):75-82. Review.PMID: 7816850

On the construction of computer models of proteins by the extension of crystallographic structures. Feldmann RJ, Bing DH, Potter M, Mainhart C, Furie B, Furie BC, Caporale LH.Ann N Y Acad Sci. 1985;439:12-43. PMID: 3859237 

.Is there a higher level genetic code that directs evolution?
Caporale LH.Mol Cell Biochem. 1984 Sep;64(1):5-13.PMID: 6493222